Degree Requirements and Course Listings
Course requirements will vary somewhat depending upon the student's previous training. Coursework requirements for the Doctor of Philosophy (Ph.D.) Degree in this Department are designed for a strong orientation in natural products research with flexibility for emphasis on the various aspects of chemistry, pharmacology or some other biological science. The guidelines established represent the minimal program of required courses.
A student who has NOT had pharmacognosy courses equivalent to PHCG 421 and 422, will be expected to audit these courses during his/her first year in the pharmacognosy graduate program. He/she will be expected to attend all lectures and take all examinations. An undergraduate course in Biochemistry will also be prerequisite; otherwise, the student will be required to take Chemistry 471 and 473 (Biochemistry, 3 hrs. ea.).
The Core Curriculum for a Master's Degree in Pharmaceutical Sciences-Pharmacognosy and the Doctor of Philosophy Degree in Pharmacognosy includes the following:
The Ph.D. Candidate will present a minimum of 36 hours of credit in course work past the Bachelor's in addition to 18 hours of credit in Dissertation, (PHCG 797). The Ph.D. candidate will take at least four additional 500 or 600 level courses to be selected by the student and their advisor/committee. These courses may be selected from a variety of fields of study, including Pharmacognosy, Pharmacology, Biochemistry, Medicinal Chemistry, Organic Chemistry, Botany, Microbiology, Marine Biology, or other approved electives.
The Master's candidate will present a minimum of 24 hours of credit in course work past the Baccalaureate in addition to 6 hours in thesis (PHCG 697). The student will need to select at least two additional elective courses.
All students (M.S. or Ph.D.) will normally register for 13 total hours each semester, at least one unit each semester must be the departmental seminar (PHCG 543, PHCG 544/PHCG 643, PHCG 644).
Graduate courses emphasize the chemistry and biology of natural products; organic chemistry of drugs and related chemicals; the mechanisms of drug actions; the isolation, purification, analysis, structure determination, biosynthesis and synthesis of naturally occurring substances; structure-activity relationships of bioactive substances; analytical procedures involving drugs and their metabolites, and the interactions of chemical leads with biological systems. Click on "Course Listing" for a complete list of Pharmacognosy courses.
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CHEM 471, 473. Biochemistry. Chemistry of biological macromolecules and their control of life processes. (3, 3 hours).
MEDC 501. Survey of Organic Medicinal Chemistry. Organic medicinal agents in current use: names, synthesis, and chemical pharmacological properties. (3 hours).
MEDC 502. Survey of Organic Medicinal Chemistry. Continuation of Medicinal Chemistry 501, with emphasis on cardiovascular and renal systems, endocrinology and chemotherapeutic agents. (3 hours).
PHCG 421. Pathogenesis and Etiology of Infectious Diseases. This course covers all aspects of infectious diseases, including etiology, epidemiology, and characteristics of disease-causing pathogens, host-pathogen interactions, symptoms and prognosis of specified infectious diseases. Prerequisite: MEDC 317. (3 hours).
PHCG 422. Natural Product Derived Pharmaceuticals. This course covers all aspects of natural products used as pharmaceuticals including both plant derived and microbial derived (antibiotics). Prerequisites: PHCG 421, MEDC 324, PHCL 343. (4 hours).
PHCG 522. Cultivation and Processing of Medicinal Plants. Cultivation, drying, and milling of plants yielding medicinal substances. (2 hours).
PHCG 541, 542. Problems in Pharmacognosy. Individual investigation of problems of current interest in Pharmacognosy. (1-4, 1-4 hours).
PHCG 543, 544. Seminar on Topics of Interest in Natural Products Chemistry. (1, 1 hour).
PHCG 620. Selected Topics in Pharmacognosy. An in-depth discussion of recent advances in knowledge of plant and animal materials with biological properties of interest to pharmaceutical scientists. (May be repeated once for credit). (3 hours).
PHCG 627, 628. Natural Product Chemistry. A comprehensive consideration of the chemistry and pharmacology of those plant constituents important because of their biological activity. Included are the bread classes, the alkaloids, the terpenoids, the steroids, the flavanoids, and other related groups. (3, 3 hours).
PHCG 631. Analysis of Natural Product Drugs. A discussion of techniques used for identification and determination of structure of substances of natural origin. Included for discussion are isolation techniques, chromatographic techniques, and micro techniques. (3 hours).
PHCG 632. Analysis of Natural Product Drugs. A discussion of techniques used for identification and determination of structure of substances of natural origin. Included for discussion are physical methods and spectroscopic techniques of structure elucidation. (3 hours).
PHCG 633. Analysis of Natural Product Drugs. A discussion of Fourier-transform nuclear magnet resonance techniques including 2D-NMR for the determination of structure of substances of natural origin. Prerequisite: 632. (3 hours).
PHCG 634. Biosynthesis of Plant Constituents. A study of the biosynthetic pathways producing physiologically active products found in natural sources. (3 hours).
PHCG 636. Fermentation Chemistry. Chemical aspects of the production of pharmaceutically and economically important substances by microorganisms. (3 hours).
PHCG 643, 644. Seminar on Current Topics of Interest in Natural Products Chemistry. (1, 1 hour). (Z grade).
PHCG 697. Thesis. (1-6 hours).
PHCG 797. Dissertation. (1-18 hours).