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Department of Medicinal Chemistry
Robert J. Doerksen Teaching

Teaching

  • In Fall 2009 (August to December, 2009), I am teaching:
    • part of MEDC 416 Medicinal Chemistry of Therapeutic Agents I (which also serves as a graduate course, MEDC 501)
    • the graduate course MEDC 611 Drug Action and Design I: Introduction to Computer-Aided Ligand Design
  • In Spring 2008 (January to May, 2008), I taught:
    • the graduate course MEDC 612 Drug Action and Design II: QSAR in Drug Design
    • part of MEDC 417 Medicinal Chemistry of Therapeutic Agents II (which also serves as a graduate course, MEDC 502)
  • In Fall 2008 (August to December, 2008), I taught:
    • part of MEDC 416 Medicinal Chemistry of Therapeutic Agents I (which also serves as a graduate course, MEDC 501)
  • In Spring 2008 (January to May, 2008), I taught:
    • the graduate course MEDC 612 Drug Action and Design II: QSAR in Drug Design
    • part of MEDC 417 Medicinal Chemistry of Therapeutic Agents II (which also serves as a graduate course, MEDC 502)
  • In Fall 2007 (August to December, 2007), I taught:
    • the graduate course MEDC 611 Drug Action and Design I: Introduction to Computer-Aided Ligand Design
    • part of MEDC 416 Medicinal Chemistry of Therapeutic Agents I (which also serves as a graduate course, MEDC 501)
  • In Spring 2007 (January to May, 2007), I taught:
    • the graduate course MEDC 612 Drug Action and Design II: QSAR in Drug Design
    • part of MEDC 417 Medicinal Chemistry of Therapeutic Agents II (which also serves as a graduate course, MEDC 502)
    • the graduate seminar courses MEDC 544 and MEDC 644, Seminar on Current Medicinal Chemistry Topics
  • In Fall 2006 (August to December, 2006), I taught:
    • part of MEDC 416 Medicinal Chemistry of Therapeutic Agents I (which also serves as a graduate course, MEDC 501)
    • the graduate seminar courses MEDC 543 and MEDC 643, Seminar on Current Medicinal Chemistry Topics
  • In Spring 2006 (January to May, 2006), I taught:
    • the graduate seminar courses MEDC 544 and MEDC 644, Seminar on Current Medicinal Chemistry Topics
  • In Fall 2005 (August to December, 2005), I taught:
    • the graduate course MEDC 611 Drug Action and Design I: Introduction to Computer-Aided Ligand Design
    • a new graduate course, MEDC 541. Problems in Medicinal Chemistry: Advanced Computational Methods for Medicinal Chemistry
    • the graduate seminar courses MEDC 543 and MEDC 643, Seminar on Current Medicinal Chemistry Topics
  • In Spring 2005 (January to May, 2005), I taught:
    • the graduate course MEDC 612 Drug Action and Design II: QSAR in Drug Design
  • In Fall 2004 (August to December, 2005), I taught:
    • the graduate course Medc 611 Drug Action & Design I: Introduction to Computer-Aided Ligand Design

Course Listings

  • # MEDC 416. Medicinal Chemistry of Therapeutic Agents I. An introduction to the chemical and physical properties of medicinal agents. Discussion of relationships of structural properties of drugs to pharmacological properties, absorption, distribution and metabolism profiles, chemical stability, mechanism of action and clinically significant drug interactions.
  • # MEDC 417. Medicinal Chemistry of Therapeutic Agents II. An introduction to the chemical and physical properties of medicinal agents. Discussion of relationships of structural properties of drugs to pharmacological properties, absorption, distribution and metabolism profiles, chemical stability, mechanism of action and clinically significant drug interactions.
  • # MEDC 501. Advanced Medicinal Chemistry I. Advanced study of organic medicinal agents with emphasis on names, synthesis, chemical properties, and pharmacological properties. Readings in the current literature required.
  • # MEDC 502. Advanced Medicinal Chemistry II. Advanced study of organic medicinal agents with emphasis on names, synthesis, chemical properties, and pharmacological properties. Readings in the current literature required.
  • # MEDC 611. Drug Action and Design I. Introduction to Computer-Aided Ligand Design. Modern molecular modeling methods and techniques as they pertain to molecular design and the simulation of molecular properties and interactions. Examples include modeling of small molecules at the level of mechanics calculations up to ab initio calculations; homology modeling of proteins and related validation methods; docking interactions of ligands and receptors. (3)
  • # MEDC 612. Drug Action and Design II. Quantitative Structure-Activity Relationships in Drug Design. Introduction to simple mathematical models of drug action (2D-QSAR) and application of the concepts to the use of computer-aided drug design to develop 3D pharmacophore models based on quantitative structure-activity relationships (3D-QSAR). (3)
  • # MEDC 541. Problems in Medicinal Chemistry: Advanced Computational Methods for Medicinal Chemistry. An advanced graduate course consisting of learning and using advanced computational methods relevant to medicinal chemistry. (3, 1).
  • # MEDC 543, MEDC 544. Seminar on Current Medicinal Chemistry Topics. A seminar consisting of presentations by faculty, graduate students, B.S. Pharmaceutical Science/Medicinal Chemistry track students and invited speakers. (1, 1).
  • # MEDC 643, MEDC 644. Seminar on Current Pharmaceutical Topics. (1, 1). (Z grade)

Theses and Dissertations

  • Pankaj R. Daga, Medicinal Chemistry (Robert J. Doerksen, supervisor), dissertation in progress
  • Gang Fu, Medicinal Chemistry (Robert J. Doerksen, supervisor), dissertation in progress
  • Khaled Elokely, Medicinal Chemistry (Robert J. Doerksen, supervisor), dissertation in progress
  • Bei Cao, Chemistry & Biochemistry (Gregory S. Tschumper, supervisor), dissertation in progress
  • Shawna Stoddard, Chemistry & Biochemistry (Randy M. Wadkins, supervisor), dissertation in progress
  • Sivaprakasam Prasanna, Medicinal Chemistry (Robert J. Doerksen, supervisor), dissertation completed (4/15/2009)
  • S. Anand, Medicinal Chemistry (John M. Rimoldi, supervisor), dissertation completed (5/2008)
  • Nakul Telang, Medicinal Chemistry (Mitchell A. Avery, supervisor), dissertation completed (2008)
  • Neha Vyas Philip, Medicinal Chemistry (Christopher R. McCurdy, supervisor), dissertation completed (4/20/2007)
  • Ashok Philip, Medicinal Chemistry (Christopher R. McCurdy, supervisor), dissertation completed (8/21/2006)
  • Cassia Mizuno, Medicinal Chemistry (Mitchell A. Avery, supervisor), dissertation completed (5/5/2006)

Undergraduate Honors and Senior Reports

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