Earlier Publications of
Professor Christopher R. McCurdy
2007
Singh, N.; Avery,
M.A.; McCurdy, C.R. Toward Mycobacterium
tuberculosis DXR Inhibitor
Design: Homology Modeling, Docking Studies, and Molecular Dynamics
Simulations. Journal of Computer-Aided Molecular Design, 2007, 21,
511-522. Web Published 9-14-2007. DOI:
10.1007/s10822-007-9132-0
Philip, A.E.;
Poupaert, J.H.; Cheve, G.; Muccioli, G; Lambert, D.; McCurdy, C.R. Structure-Activity Relationships of
Phenytoinergic Antiepileptic Drugs Related to Ameltolide. Medicinal
Chemistry Research, 2007, 15, 130-135. Web Published 7-26-2007. DOI:
10.1007/s00044-007-9016-9
Willmore-Fordham C.B.;
Krall, D.M., McCurdy, C.R.;
Kinder, D.H. The hallucinogen derived from Salvia divinorum, salvinorin A, has kappa opioid agonist
discriminative stimulus effects in rats. Neuropharmacology 2007, 53, 481-486. Web Published 6-27-2007.
DOI: 10.1016/j.neuropharm.2007.06.008
Martinez, M.N.;
Bonate, P.; Chapman, R.L.; De Groot, A.; D'Souza, S.; Ghilazi, N.; Gray, V.;
Gupta, V.K.; Huynh-Ba, K.; Iyer, S.; Jayatilaka, A.; Joshi, A.; Karnes, H.T.;
Kahn, M.; Liu, P.; Lunte, C.; McCurdy, C.R.; Morris, M.E.; Norris, K.J.; Ramsey, P.; Sehgal, S.;
Zahn, M. 2007 Highlights of Advances in Pharmaceutical Sciences: An
American Association of Pharmaceutical Scientists (AAPS) Perspective. AAPS
Journal, 2007, 9,
Article 24. DOI: 10.1208/aapsj0902024
Prabhu-Haris, S.;
Zhang, Y.; Le Bourdonnec, B.; McCurdy, C.R.; Portoghese, P.S. o-Naphthalenedicarboxaldehyde Derivative of
7'-Aminonaltrindole as a Selective Delta-Opioid Receptor Affinity Label. Journal
of Medicinal Chemistry, 2007, 50, 3392-3396. Web Published 6-8-2007. DOI:
10.1021/jm061194h
Dayan, F.E.; Duke,
S.O.; Sauldubois, A.; Singh, N.; McCurdy, C.; Cantrell, C. p-Hydroxyphenylpyruvate Dioxygenase is a Target Site
for beta-Triketone Phytochemicals. Phytochemistry, 2007, 68,
2004-2014. Web Published
3-27-2007. DOI: 10.1016/j.phytochem.2007.01.026
Singh, N.; Cheve, G.;
Avery, M.A.; McCurdy, C.R.
Targeting the Methyl Erythritol Phosphate (MEP) Pathway for Novel Antimalarial,
Antibacterial and Herbicidal Drug Discovery: Inhibition of
1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase (DXR) Enzyme. Current
Pharmaceutical Design, 2007, 13, 1161-1177. DOI: 10.2174/138161207780618939
2006
Singh, N.; Cheve, G.;
Ferguson, D.M.; McCurdy, C.R.
A Combined Ligand-Based and Target-Based Drug Design Approach for G-Protein
Coupled Receptors: Application to Salvinorin A, A Selective Kappa Opioid
Receptor Agonist. Journal of Computer-Aided Molecular Design, 2006, 20,
471-493. Web Published 9-29-2006. DOI: 10.1007/s10822-006-9067-x
Singh, N.; Cheve, G.;
Avery, M.A.; McCurdy, C.R. Comparative
Protein Modeling of 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase Enzyme from
Plasmodium falciparum: A Potential
Target for Antimalarial Drug Discovery. Journal of Chemical
Information and Modeling, 2006, 46, 1360-1370. Web Published 4-4-2006.
DOI: 10.1021/ci050523w
Kane, B.E.; Nieto, M.J.; McCurdy,
C.R.; Ferguson, D.M. A Unique
Binding Epitope for Salvinorin A, a Non-Nitrogenous Kappa Opioid Receptor
Agonist. FEBS Journal,
2006, 273, 1966-1974. Web
Published 4-5-2006. DOI: 10.1111/j.1742-4658.2006.05212.x
Vyas, N.;
Mollereau-Manaute, C.; Cheve, G.; McCurdy, C.R. Structure Activity Relationships of
Neuropeptide FF and Related Peptidic and Non-Peptidic Derivatives. Peptides, 2006, 27,
990-996. Web Published 2-21-2006. DOI:
10.1016/j.peptides.2005.07.024
McCurdy, C.R.; Sufka, K.J.; Smith, G.H.; Warnick, J.E.; Nieto, M.J.
Analgesic Profile of Salvinorin A, a Structurally Unique Kappa Opioid Receptor
Agonist. Pharmacology, Biochemistry, and Behavior, 2006, 83, 109-113. Web Published 1-23-2006.
DOI: 10.1016/j.pbb.2005.12.011
2005
Yous, S.; Wallez, V.;
Belloir, M.; Caignard, D.H.; McCurdy, C.R.; Poupaert, J.H. Novel 2(3H)-Benzohiazolones as Highly Potent and Selective Sigma-1 Receptor
Ligands. Medicinal Chemistry Research, 2005, 14,
158-168. DOI: 10.1007/s00044-005-0131-1
McCurdy, C.R. Development of Opioid Receptor Ligands.
In: Analogue-Based Drug Discovery. Eds. Fischer, J.; Ganellin, C.R., IUPAC.
Wiley-VCH, 2005. pp 259-276. ISBN: 3-527-31257-9
McCurdy, C.R.: Scully, S.S. Analgesic substances derived from
natural products (Natruceuticals). Life Sciences, 2005, 78,
476-484. Web published 10-10-2005. DOI:
10.1016/j.lfs.2005.09.006
Geldenhuys, W.J.; Lockman,
P.R.; Philip, A.E.; McAfee, J.H.; Miller, B.L.; McCurdy, C.R.; Allen, D.D. Inhibition of choline uptake by
N-cyclohexylcholine, a high affinity ligand for the choline transporter at the
Blood-Brain Barrier. Journal of Drug Targeting, 2005, 13,
259-266. DOI: 10.1080/10611860500139222
Poupaert, J.H.; Carato, P.;
McCurdy, C.R. A Simple and Effective
Method for the Thionation of Amides to Thioamides using Al2O3-supportedP4S10.
Letters in Organic Chemistry,
2005, 2, 330-333. DOI:
10.2174/1570178054038957
Warnick, J.E.; McCurdy,
C.R.; Sufka, K.J. Opiate Modulation
of Social Attachment. Behavioural Brain Research, 2005, 160,
277-285. DOI: 10.1016/j.bbr.2004.12.009
Nieto, M.; Philip, A.E.;
Poupaert, J.H.; McCurdy, C.R.
Soultion Phase Parallel Synthesis of Spirohydantoins. Journal of
Combinatorial Chemistry, 2005, 7,
258-263. Web Published 12-24-2004. DOI: 10.1021/cc049870t
Philip, A.E.; Poupeart,
J.H.; McCurdy, C.R. Opioid
Receptor Like-1 (ORL1) molecular road map to understanding ligand interaction
and selectivity. Current Topics in Medicinal Chemistry, 2005, 5, 325-340. DOI: 10.2174/1568026053544489
Zhang, Y.; McCurdy, C.R.; Metzger, T.G.; Portoghese, P.S. Specific
cross-linking of LYS233 and CYS235 in the mu opioid receptor by a reporter
affinity label. Biochemistry,
2005, 44. 2271-2275. DOI:
10.1021/bi048049v
2004
Poupaert, J.H.; Duarte, S.;
Depreux, P.; McCurdy, C.R.;
Lambert, D.L. Willgerodt-Kindlers Microwave-enhanced Synthesis of Thioamide
Derivatives. Phosphorus, Sulfur, and Silicon and the related elements. 2004, 179,
1959-1973. DOI: 10.1080/10426500490466977
2003
Poupaert, J.H.; Depreux,
P.; McCurdy, C.R. Unsymmetrical
diarylketones from electron-rich heterocyclic arenes. Monatshefte fur
Chemie (Chemical Monthly). 2003, 134,
823-830. Web Published 3-6-2003. DOI: 10.1007/s00706-002-0573-9
2002
McCurdy, C.R. Pharmacy Education: From Prescott to
Pharmacogenomics. Journal of the American Pharmaceutical Association 2002, 42,
688-691.
McCurdy, C.R.; Le Bourdonnec, B.; Metzger, T.G.; El Kouhen, R.;
Zhang, Y.; Law, P.Y.; Portoghese, P.S. Naphthalene dicarboxaldehyde as an
electrophilic fluorogenic moiety for affinity labeling: Application to opioid
receptor affinity labels with greatly improved fluorogenic properties. Journal
of Medicinal Chemistry 2002, 45,
2887-2890. Web Published 6-12-2002. DOI: 10.1021/jm015586u
2000
McCurdy, C.R.; Jones, R.M.; Portoghese, P.S. Investigation of
phenolic bioisosterism in opioids: Synthesis and biological evaluation of
3-methylsulfonamide analogues of naltrexone and oxymorphone. Organic
Letters 2000, 2, 819-821. DOI: 10.1021/ol005561+
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